Virtual Consultations
Please directly call our main office to complete your appointment
Virtual Consultations
Book Appointment

Semaglutide vs Contrave

Find out which weight loss medication is right for you

Are you unsure about the differences between Semaglutide and Contrave for weight loss? 

Understanding the unique features of these medications is key to making an informed choice for your weight management journey.

Semaglutide, sold as Ozempic and Wegovy, acts as a GLP-1 receptor agonist, reducing appetite by mimicking gut hormones.

On the other hand, Contrave combines naltrexone and bupropion to curb hunger and cravings.

While both have shown weight loss effectiveness, individual responses may vary.

Exploring their mechanisms of action, potential side effects, and impact on weight management will help you decide which medication aligns with your health goals.

This article offers essential information to guide your decision-making process regarding Semaglutide and Contrave.

Get Your Health Back On Track With Our Medical Weight Loss Management Programs

Let Dr. V and our staff help you discover the true beauty hiding within. Book your consultation with us today to learn more about your ideal cosmetic treatment.

request your consultation

What is Semaglutide?

You should familiarize yourself with how semaglutide functions in the body to understand its role in weight management.

Semaglutide, available as Ozempic and Wegovy, is a GLP-1 receptor agonist that mimics gut hormones, signaling fullness to the brain and reducing appetite.

Studies show it's more effective for weight loss compared to Contrave.

What is Contrave?

Contrave is a combination of naltrexone and bupropion, aimed to reduce hunger and cravings. Studies suggest it aids in weight loss, with common side effects like nausea and constipation.

Cost varies based on insurance coverage, and a monthly subscription program is available for eligible patients, offering the medication for $99 or less per month.

Mechanisms of Action Compared

Comparing the mechanisms of action between Semaglutide and Contrave reveals how these medications target weight management in distinct ways, impacting hunger, cravings, and overall body weight.

Mechanism of ActionSemaglutide (Ozempic and Wegovy)Contrave
TypeGLP-1 receptor agonist, incretin mimeticCombination: bupropion and naltrexone
EffectAppetite suppressant, enhances insulin sensitivityReduces hunger and cravings

Efficacy in Weight Loss

semaglutide vs contrave

The medications' efficacy in weight loss varies based on individual factors and adherence to treatment plans.

Both semaglutide and Contrave have shown effectiveness in weight management.

Semaglutide, with its mimicking of gut hormones, has demonstrated greater weight loss results compared to Contrave in clinical studies. However, long-term results may differ.

Adhering to calorie restriction and individualized treatment plans is crucial for achieving successful weight loss with either anti-obesity medication.

Potential Side Effects

Your care team will discuss potential side effects of both medications with you to ensure informed decision-making.

  • Nausea
  • Constipation
  • Headache
  • Dizziness
  • Rare serious effects

It's essential to understand the risks and warnings associated with medications like naltrexone and their potential impact on individual results, especially when addressing obesity.

Be sure to consult with your healthcare provider to make the best decision for your health.

Semaglutide and Contrave: Dosage and Administration

Contrave pills

How frequently should you administer semaglutide and contrave for weight management?

Semaglutide, available as Ozempic and Wegovy, is injected subcutaneously once weekly. It's often combined with diet and exercise changes for type 2 diabetes.

Contrave, a combination of naltrexone and bupropion, is taken orally as tablets, gradually increasing to 2 tablets twice daily.

Both medications should be used as prescribed by a medical provider and in conjunction with lifestyle changes and diet.

FDA Approval and Indications for Semaglutide and Contrave

If you have been considering the use of semaglutide or Contrave for weight management, it's important to understand the FDA approval and indications for these medications.

  • Both medications are FDA-approved for use in adults with obesity or overweight and weight-related conditions.
  • Scientific evidence supports their benefits in managing chronic conditions.
  • Reviews from medical professionals can provide valuable insights.
  • Understanding the indications can help in making informed decisions.
  • Consulting a healthcare provider is crucial for personalized treatment.

Cost and Insurance Considerations

Cost and insurance considerations play a crucial role in determining the accessibility of semaglutide and Contrave for individuals seeking effective weight management options. 

When considering cost and insurance coverage, it is important to consult with your doctor to create a personalized plan that aligns with your metabolic health needs. 

Patient testimonials can also offer valuable insights into the affordability and effectiveness of these medications.

ConsiderationSemaglutide (Wegovy)Contrave
CostVaries based on insurance coverageVaries based on insurance coverage
Insurance CoverageCoverage may varyCoverage may vary
Affordability TestimonialsPositive testimonials regarding affordabilityMixed testimonials regarding affordability

Drug Interactions and Precautions

Discuss with your healthcare provider any potential drug interactions and precautions to be aware of when considering the use of Semaglutide or Contrave for weight management.

  • Semaglutide and Contrave may interact with other medications, affecting their effectiveness.
  • Precautions include monitoring for low blood sugar symptoms and staying hydrated.

Consult a healthcare professional before combining these medications with others.

Regular check-ups are essential while using Semaglutide or Contrave.

Inform your care team of any changes in your health status.

Making the Right Choice

When considering weight management medications, routinely consult with your healthcare provider to make the right choice for your individual needs and health conditions. 

Below is a comparison table to help you make an informed decision.

CriteriaSemaglutide (Wegovy)Contrave
Weight loss14.9% over 68 weeks8.1% over 56 weeks
Side effectsGastrointestinalNausea, constipation
FDA indicationsObesity, overweightObesity, overweight

Choose the medication that best aligns with your health, fitness, and quality of life goals based on your doctor's guidance.

Schedule a Consultation with Dr. V Medical Aesthetics

Dr. V and her staff

When considering weight loss medications, it's important to weigh the benefits and potential side effects of Semaglutide and Contrave. 

Both have shown effectiveness in weight loss through different mechanisms of action.

Your individual response and health goals will ultimately guide your decision. Consult with Dr. V Medical Aesthetics today to determine which medication aligns best with your needs and preferences.


Contact - Internal Page / Blog Post

Follow Us:

Find Confidence In Your Beauty

Dr. V Medical Aesthetics is ready to help you achieve your beauty goals. Contact us today to learn more about any of our services, and exactly what our team can do for you.